ARG44072
anti-NAPRT antibody
anti-NAPRT antibody for Western blot and Human
Overview
Product Description | Rabbit Polyclonal recognizes NAPRT |
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Tested Reactivity | Hu |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | NAPRT |
Antigen Species | Human |
Immunogen | Human NAPRT recombinant protein (Position: A69-Q480). |
Conjugation | Un-conjugated |
Alternate Names | NAPRT; Nicotinate Phosphoribosyltransferase; PP3856; NAPRT1; Nicotinate Phosphoribosyltransferase Domain-Containing Protein 1; Nicotinate Phosphoribosyltransferase Domain Containing 1; FHA-HIT-Interacting Protein; NAPRTase; Nicotinic Acid Phosphoribosyltransferase; EC 6.3.4.21; EC 2.4.2.11; FHIP |
Application Instructions
Application Suggestion |
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Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
Preservative | 0.05% Sodium azide |
Stabilizer | 4% Trehalose |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q6XQN6 Human Nicotinate phosphoribosyltransferase |
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Gene Symbol | NAPRT |
Gene Full Name | Nicotinate Phosphoribosyltransferase |
Background | Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress. |
Function | Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. |
Cellular Localization | Cytoplasm |
Calculated MW | 58 kDa |
PTM | Phosphoprotein |
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