ARG63993

anti-Myosin IXB antibody

anti-Myosin IXB antibody for Western blot and Human

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes Myosin IXB
Tested Reactivity Hu
Tested Application WB
Specificity This antibody is expected to recognise both reported isoforms (NP_004136.2; NP_001123537.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name Myosin IXB
Antigen Species Human
Immunogen C-KNDFEPVKQSKAQ
Conjugation Un-conjugated
Alternate Names Unconventional myosin-9b; MYR5; CELIAC4; Unconventional myosin-IXb

Application Instructions

Application Suggestion
Tested Application Dilution
WB2 - 6 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4650 Human MYO9B

Swiss-port # Q13459 Human Unconventional myosin-IXb

Background This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Research Area Signaling Transduction antibody
Calculated MW 243 kDa

Images (1) Click the Picture to Zoom In

  • ARG63993 anti-Myosin IXB antibody WB image

    Western Blot: Human Liver lysate (35 µg protein in RIPA buffer) stained with ARG63993 anti-Myosin IXB antibody at 2 µg/ml dilution.