ARG66552

anti-MYBPC1 antibody

anti-MYBPC1 antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes MYBPC1
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MYBPC1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the center region of Human MYBPC1.
Conjugation Un-conjugated
Alternate Names LCCS4; MYBPCC; Slow MyBP-C; C-protein, skeletal muscle slow isoform; MYBPCS; Myosin-binding protein C, slow-type

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol.
Preservative 0.01% Sodium azide
Stabilizer 30% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 362867 Rat MYBPC1

GeneID: 4604 Human MYBPC1

Swiss-port # Q00872 Human Myosin-binding protein C, slow-type

Swiss-port # Q63518 Rat Myosin-binding protein C, slow-type

Gene Symbol MYBPC1
Gene Full Name myosin binding protein C, slow type
Background This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Function Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. [UniProt]
Calculated MW 128 kDa

Images (1) Click the Picture to Zoom In

  • ARG66552 anti-MYBPC1 antibody WB image

    Western blot: U2OS, Mouse skeletal muscle and Rat skeletal muscle lysates stained with ARG66552 anti-MYBPC1 antibody.