ARG66836
anti-MUC13 / Mucin 13 antibody
anti-MUC13 / Mucin 13 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MUC13 / Mucin 13 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MUC13 / Mucin 13 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide between aa. 421-470 of Human MUC13 / Mucin 13. |
| Conjugation | Un-conjugated |
| Alternate Names | MUC-13; DRCC1; Mucin-13; Down-regulated in colon cancer 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MUC13 |
| Gene Full Name | mucin 13, cell surface associated |
| Background | Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008] |
| Function | Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Apical cell membrane. Secreted. Note=Also exists as a soluble form. [UniProt] |
| Calculated MW | 55 kDa |
| PTM | Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds. Highly N-glycosylated. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG66836 anti-MUC13 / Mucin 13 antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG66836 anti-MUC13 / Mucin 13 antibody. The picture on the right is blocked with the synthetic peptide.
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ARG66836 anti-MUC13 / Mucin 13 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon carcinoma tissue stained with ARG66836 anti-MUC13 / Mucin 13 antibody. The picture on the right is blocked with the synthetic peptide.
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ARG66836 anti-MUC13 / Mucin 13 antibody WB image
Western blot: COLO205, 293 and HeLa cell lysates stained with ARG66836 anti-MUC13 / Mucin 13 antibody. The lane on the right is blocked with the synthetic peptide.
