ARG58754
anti-MSTN / GDF8 antibody
anti-MSTN / GDF8 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MSTN / GDF8 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MSTN / GDF8 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 9-38 of Human MSTN / GDF8. |
| Conjugation | Un-conjugated |
| Alternate Names | GDF-8; Myostatin; GDF8; MSLHP; Growth/differentiation factor 8 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | K562 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MSTN |
| Gene Full Name | myostatin |
| Background | The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. [provided by RefSeq, Jul 2008] |
| Function | Acts specifically as a negative regulator of skeletal muscle growth. [UniProt] |
| Calculated MW | 43 kDa |
Images (2) Click the Picture to Zoom In
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ARG58754 anti-MSTN / GDF8 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human skeletal muscle tissue stained with ARG58754 anti-MSTN / GDF8 antibody.
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ARG58754 anti-MSTN / GDF8 antibody WB image
Western blot: 20 µg of K562 cell lysate stained with ARG58754 anti-MSTN / GDF8 antibody at 1:2000 dilution.
