ARG42940
anti-MSRB3 antibody
anti-MSRB3 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes MSRB3 |
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Tested Reactivity | Hu, Ms, Rat |
Tested Application | ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | MSRB3 |
Antigen Species | Human |
Immunogen | Recombinant fusion protein corresponding to aa. 1-185 of Human MSRB3 (NP_001026849.1). |
Conjugation | Un-conjugated |
Alternate Names | EC 1.8.4.-; DFNB74; MsrB3; Methionine-R-sulfoxide reductase B3 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | Mouse testis | ||||||
Observed Size | ~ 22 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q8BU85 Mouse Methionine-R-sulfoxide reductase B3, mitochondrial Swiss-port # Q8IXL7 Human Methionine-R-sulfoxide reductase B3 |
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Gene Symbol | MSRB3 |
Gene Full Name | methionine sulfoxide reductase B3 |
Background | The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010] |
Function | Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing. [UniProt] |
Cellular Localization | Isoform 1: Endoplasmic reticulum. Isoform 2: Mitochondrion. [UniProt] |
Calculated MW | 21 kDa |
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