ARG40458

anti-MSRA antibody

anti-MSRA antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes MSRA
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MSRA
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 24-235 of Human MSRA (NP_036463.1).
Conjugation Un-conjugated
Alternate Names EC 1.8.4.11; Peptide Met; O; Peptide-methionine; Protein-methionine-S-oxide reductase; Mitochondrial peptide methionine sulfoxide reductase; S; PMSR

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat kidney
Observed Size 26 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 110265 Mouse MSRA

GeneID: 29447 Rat MSRA

GeneID: 4482 Human MSRA

Gene Symbol MSRA
Gene Full Name methionine sulfoxide reductase A
Background This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Function Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. [UniProt]
Cellular Localization Isoform 1: Mitochondrion. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm. Nucleus. Isoform 5: Cytoplasm. Membrane; Lipid-anchor. [UniProt]
Calculated MW 26 kDa

Images (2) Click the Picture to Zoom In

  • ARG40458 anti-MSRA antibody ICC/IF image

    Immunofluorescence: U2OS cells stained with ARG40458 anti-MSRA antibody.

  • ARG40458 anti-MSRA antibody WB image

    Western blot: 25 µg of Rat kidney lysate stained with ARG40458 anti-MSRA antibody at 1:1000 dilution.