ARG63725

anti-MOG / Myelin oligodendrocyte glycoprotein antibody

anti-MOG / Myelin oligodendrocyte glycoprotein antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes MOG / Myelin oligodendrocyte glycoprotein
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Pig
Tested Application IHC-P, WB
Specificity This antibody is expected to recognise NP_996532.2 (isf a1), NP_996535.2 (isf a2) and NP_001008229.1 (isf a3)
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name MOG / Myelin oligodendrocyte glycoprotein
Antigen Species Human
Immunogen C-AGQFLEELRNPF
Conjugation Un-conjugated
Alternate Names BTNL11; BTN6; NRCLP7; MOGIG2; Myelin-oligodendrocyte glycoprotein

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P5 µg/ml
WB0.03 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4340 Human MOG

Swiss-port # Q16653 Human Myelin-oligodendrocyte glycoprotein

Background The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 28 kDa

Images (2) Click the Picture to Zoom In

  • ARG63725 anti-MOG / Myelin oligodendrocyte glycoprotein antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63725 anti-MOG / Myelin oligodendrocyte glycoprotein antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63725 anti-MOG / Myelin oligodendrocyte glycoprotein antibody WB image

    Western blot: 30 µg of Human brain lysate (in RIPA buffer) stained with ARG63725 anti-MOG / Myelin oligodendrocyte glycoprotein antibody at 0.03 µg/ml dilution and incubated at RT for 1 hour.