ARG55535
anti-MMP9 antibody [S51-82]
anti-MMP9 antibody [S51-82] for Immunohistochemistry,Western blot and Human,Mouse,Rat
Brain Injury IHC Study antibody
Overview
| Product Description | Mouse Monoclonal antibody [S51-82] recognizes MMP9 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | S51-82 |
| Isotype | IgG2a |
| Target Name | MMP9 |
| Antigen Species | Rat |
| Immunogen | Fusion protein (full-length) of Rat MMP9 (NP_112317.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Matrix metalloproteinase-9; MMP-9; Gelatinase B; GELB; 92 kDa gelatinase; EC 3.4.24.35; 92 kDa type IV collagenase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Mmp9 |
| Gene Full Name | matrix metallopeptidase 9 |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008] |
| Function | Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). [UniProt] |
| Highlight | Related products: MMP9 antibodies; MMP9 ELISA Kits; MMP9 Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: Rat MMP9 ELISA Kit is available in arigo |
| Research Area | Brain Injury IHC Study antibody |
| Calculated MW | 78 kDa |
| PTM | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. |
Images (1) Click the Picture to Zoom In
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ARG55535 anti-MMP9 antibody [S51-82] WB image
Western blot: Adult rat brain stained with ARG55535 anti-MMP9 antibody [S51-82] (Two Lanes). Bands of ~92 and 82 kDa (proenzyme and active enzyme) are detected.
