ARG44179
anti-MMP19 antibody
anti-MMP19 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MMP19 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MMP19 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human MMP19 |
| Conjugation | Un-conjugated |
| Protein Full Name | Matrix metalloproteinase-19 |
| Alternate Names | MMP19; Matrix Metallopeptidase 19; RASI-1; MMP18; Matrix Metalloproteinase RASI; Matrix Metalloproteinase-19; Matrix Metalloproteinase-18; Matrix Metalloproteinase-Beta19; Matrix Metalloproteinase 19; EC 3.4.24.- ; MMP-19; MMP-18; CODA; RASI |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MMP19 |
| Gene Full Name | Matrix Metallopeptidase 19 |
| Background | This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. |
| Function | Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin. |
| Cellular Localization | Extracellular matrix, Secreted |
| Calculated MW | 57 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein, Zymogen |
Images (5) Click the Picture to Zoom In
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ARG44179 anti-MMP19 antibody IHC-P image
Immunohistochemistry: Human glioma stained with ARG44179 anti-MMP19 antibody at 2 μg/mL dilution.
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ARG44179 anti-MMP19 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44179 anti-MMP19 antibody at 5 μg/mL dilution.
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ARG44179 anti-MMP19 antibody WB image
Western blot: 293T and Hela stained with ARG44179 anti-MMP19 antibody at 0.25 μg/mL dilution.
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ARG44179 anti-MMP19 antibody FACS image
Flow Cytometry: 293T stained with ARG44179 anti-MMP19 antibody at 1 μg/1x10^6 cells dilution.
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ARG44179 anti-MMP19 antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44179 anti-MMP19 antibody at 2 μg/mL dilution.
