ARG66407
anti-MMP10 antibody
anti-MMP10 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MMP10 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MMP10 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 330-410 of Human MMP10. |
| Conjugation | Un-conjugated |
| Alternate Names | SL-2; STMY2; Transin-2; EC 3.4.24.22; Matrix metalloproteinase-10; MMP-10; Stromelysin-2 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | ~ 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MMP10 |
| Gene Full Name | matrix metallopeptidase 10 |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
| Function | Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
| Calculated MW | 54 kDa |
Images (3) Click the Picture to Zoom In
-
ARG66407 anti-MMP10 antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG66407 anti-MMP10 antibody (green). The picture on the right is blocked with the synthetic peptide.
-
ARG66407 anti-MMP10 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung carcinoma stained with ARG66407 anti-MMP10 antibody. The picture on the right is blocked with the synthetic peptide.
-
ARG66407 anti-MMP10 antibody WB image
Western blot: 35 µg of A549 cell lysate stained with ARG66407 anti-MMP10 antibody at 1:1000 dilution.
