ARG44706
anti-MMAB antibody
anti-MMAB antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes MMAB |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | MMAB |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | ATR; cob; cblB; CFAP23; Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial; EC 2.5.1.17; Cob(I)alamin adenosyltransferase; Methylmalonic aciduria type B protein |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96EY8 Human Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial |
|---|---|
| Gene Symbol | MMAB |
| Gene Full Name | methylmalonic aciduria (cobalamin deficiency) cblB type |
| Background | This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found. [provided by RefSeq, Apr 2011] |
| Cellular Localization | Mitochondrion. |
| Calculated MW | 27 kDa |
| PTM | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
Images (2) Click the Picture to Zoom In
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ARG44706 anti-MMAB antibody IHC-P image
Immunohistochemistry: Human liver stained with ARG44706 anti-MMAB antibody at 5 µg/mL dilution.
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ARG44706 anti-MMAB antibody IP image
Immunoprecipitation: A549 lysate immunoprecipitated with 2.5 µg of ARG44706 anti-MMAB antibody.
