ARG56796

anti-MIP4 antibody (Biotin)

anti-MIP4 antibody (Biotin) for ELISA,Western blot and Human

Overview

Product Description Biotin-conjugated Rabbit Polyclonal antibody recognizes MIP4
Tested Reactivity Hu
Tested Application ELISA, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MIP4
Antigen Species Human
Immunogen E.coli derived Recombinant Human MIP-4.
(QVGTNKELCC LVYTSWQIPQ KFLVDYSETS PQCPKPGVIL LTKRGRQICA DPNKKWVQKY ISDLKLNA)
Conjugation Biotin
Alternate Names Small-inducible cytokine A18; 3-69; PARC; Alternative macrophage activation-associated CC chemokine 1; Macrophage inflammatory protein 4; SCYA18; Dendritic cell chemokine 1; CC chemokine PARC; 4-69; 1-68; C-C motif chemokine 18; DC-CK1; AMAC1; Pulmonary and activation-regulated chemokine; AMAC-1; DCCK1; MIP-4; CKb7

Application Instructions

Application Suggestion
Tested Application Dilution
ELISADirect: 0.25 - 1.0 µg/ml
Sandwich: 0.25 - 1.0 µg/ml with ARG56687 as a capture antibody
WB0.1 - 0.2 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified by affinity chromatography.
Buffer PBS (pH 7.2)
Concentration 1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6362 Human CCL18

Swiss-port # P55774 Human C-C motif chemokine 18

Gene Symbol CCL18
Gene Full Name chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
Background This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
Function Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. [UniProt]
Calculated MW 10 kDa
PTM The Cys-30/Cys-54 disulfide bond is required for activity.

Images (2) Click the Picture to Zoom In

  • ARG56796 anti-MIP4 antibody (Biotin) WB image

    Western blot: 250 - 0.24 ng of Human MIP-4 stained with ARG56796 anti-MIP4 antibody (Biotin), under reducing conditions.

  • ARG56796 anti-MIP4 antibody (Biotin) WB image

    Western blot: 250 - 0.24 ng of Human MIP-4 stained with ARG56796 anti-MIP4 antibody (Biotin), under non-reducing conditions.