ARG56687
anti-MIP4 antibody
anti-MIP4 antibody for ELISA,Neutralizing,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MIP4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, Neut, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MIP4 |
| Antigen Species | Human |
| Immunogen | E.coli derived Recombinant Human MIP-4 (CCL18). (QVGTNKELCC LVYTSWQIPQ KFLVDYSETS PQCPKPGVIL LTKRGRQICA DPNKKWVQKY ISDLKLNA) |
| Conjugation | Un-conjugated |
| Alternate Names | Small-inducible cytokine A18; 3-69; PARC; Alternative macrophage activation-associated CC chemokine 1; Macrophage inflammatory protein 4; SCYA18; Dendritic cell chemokine 1; CC chemokine PARC; 4-69; 1-68; C-C motif chemokine 18; DC-CK1; AMAC1; Pulmonary and activation-regulated chemokine; AMAC-1; DCCK1; MIP-4; CKb7 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL18 |
| Gene Full Name | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| Background | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014] |
| Function | Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. [UniProt] |
| Calculated MW | 10 kDa |
| PTM | The Cys-30/Cys-54 disulfide bond is required for activity. |
Images (2) Click the Picture to Zoom In
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ARG56687 anti-MIP4 antibody WB image
Western blot: 250 - 0.24 ng of Human MIP-4 stained with ARG56687 anti-MIP4 antibody, under reducing conditions.
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ARG56687 anti-MIP4 antibody WB image
Western blot: 250 - 0.24 ng of Human MIP-4 stained with ARG56687 anti-MIP4 antibody, under non-reducing conditions.
