ARG44571
anti-MICALL1 antibody
anti-MICALL1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MICALL1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MICALL1 |
| Antigen Species | Human |
| Immunogen | Human MICALL1 recombinant protein (aa. sequence: R192-K747). |
| Conjugation | Un-conjugated |
| Alternate Names | MICALL1; MICAL Like 1; MIRAB13; Molecule Interacting With Rab13; KIAA1668; MICAL-L1; MICAL-Like Protein 1; MICAL-Like 1; MIRab13 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Preservative | 4% Trehalose |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MICALL1 |
| Gene Full Name | MICAL Like 1 |
| Background | Enables identical protein binding activity; phosphatidic acid binding activity; and small GTPase binding activity. Involved in several processes, including plasma membrane tubulation; protein localization to endosome; and slow endocytic recycling. Located in late endosome and recycling endosome membrane. Is extrinsic component of membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth. [Uniprot] |
| Cellular Localization | Endosome, Membrane. [Uniprot] |
| Calculated MW | 93 kDa |
| PTM | Phosphoprotein. [Uniprot] |
Images (7) Click the Picture to Zoom In
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ARG44571 anti-MICALL1 antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG44571 anti-MICALL1 antibody at 2 μg/ml dilution.
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ARG44571 anti-MICALL1 antibody WB image
Western blot: MCF-7, HeLa and Hacat stained with ARG44571 anti-MICALL1 antibody at 0.5 μg/mL dilution.
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ARG44571 anti-MICALL1 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44571 anti-MICALL1 antibody at 1 μg/10^6 cells dilution.
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ARG44571 anti-MICALL1 antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG44571 anti-MICALL1 antibody at 2 μg/ml dilution.
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ARG44571 anti-MICALL1 antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG44571 anti-MICALL1 antibody at 2 μg/ml dilution.
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ARG44571 anti-MICALL1 antibody IHC-P image
Immunohistochemistry: Human placenta cancer stained with ARG44571 anti-MICALL1 antibody at 2 μg/ml dilution.
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ARG44571 anti-MICALL1 antibody IHC-P image
Immunohistochemistry: Human thyroid papillary carcinoma stained with ARG44571 anti-MICALL1 antibody at 2 μg/ml dilution.
