ARG58960
anti-MGP antibody
anti-MGP antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MGP |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MGP |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 20-103 of Human MGP (NP_000891.2). |
| Conjugation | Un-conjugated |
| Alternate Names | Cell growth-inhibiting gene 36 protein; GIG36; Matrix Gla protein; NTI; MGP; MGLAP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | U-87MG | ||||||||
| Observed Size | 12 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MGP |
| Gene Full Name | matrix Gla protein |
| Background | The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| Function | Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 12 kDa |
| PTM | Requires vitamin K-dependent gamma-carboxylation for its function. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG58960 anti-MGP antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG58960 anti-MGP antibody at 1:100 dilution.
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ARG58960 anti-MGP antibody WB image
Western blot: 25 µg of U-87MG cell lysate stained with ARG58960 anti-MGP antibody at 1:1000 dilution.
