ARG44165
anti-METTL11A antibody
anti-METTL11A antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes METTL11A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | METTL11A |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human METTL11A |
| Conjugation | Un-conjugated |
| Protein Full Name | N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
| Alternate Names | NTMT1; N-Terminal Xaa-Pro-Lys N-Methyltransferase 1; NRMT1; NRMT; METTL11A; C9orf32; AD-003; HOMT1A; X-Pro-Lys N-Terminal Protein Methyltransferase 1A; Alpha N-Terminal Protein Methyltransferase 1A; Methyltransferase-Like Protein 11A; N-Terminal RCC1 Methyltransferase; NTM1A; Chromosome 9 Open Reading Frame 32; Methyltransferase Like 11A; EC 2.1.1.244 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9BV86 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
|---|---|
| Gene Symbol | NTMT1 |
| Gene Full Name | N-Terminal Xaa-Pro-Lys N-Methyltransferase 1 |
| Background | The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200). |
| Function | Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by NTMT2-mediated monomethylation. |
| Cellular Localization | Nucleus |
| Calculated MW | 25 kDa |
| PTM | Acetylation |
Images (5) Click the Picture to Zoom In
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ARG44165 anti-METTL11A antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44165 anti-METTL11A antibody at 2 μg/mL dilution.
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ARG44165 anti-METTL11A antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44165 anti-METTL11A antibody at 5 μg/mL dilution.
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ARG44165 anti-METTL11A antibody WB image
Western blot: 293T, Hela and A549 stained with ARG44165 anti-METTL11A antibody at 0.5 μg/mL dilution.
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ARG44165 anti-METTL11A antibody FACS image
Flow Cytometry: HepG2 stained with ARG44165 anti-METTL11A antibody at 1 μg/1x10^6 cells dilution.
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ARG44165 anti-METTL11A antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44165 anti-METTL11A antibody at 2 μg/mL dilution.
