ARG66412
anti-MED6 antibody
anti-MED6 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MED6 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MED6 |
| Antigen Species | Human |
| Immunogen | Full length fusion protein of Human MED6. |
| Conjugation | Un-conjugated |
| Alternate Names | Activator-recruited cofactor 33 kDa component; Renal carcinoma antigen NY-REN-28; NY-REN-28; hMed6; Mediator of RNA polymerase II transcription subunit 6; ARC33; Mediator complex subunit 6 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | IHC-P: Human brain; WB: HeLa, PC3, 231 and Human esophagus cancer tissue |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Concentration | 1.8 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75586 Human Mediator of RNA polymerase II transcription subunit 6 |
|---|---|
| Gene Symbol | MED6 |
| Gene Full Name | mediator complex subunit 6 |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 28 kDa |
Images (1) Click the Picture to Zoom In
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ARG66412 anti-MED6 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human brain stained with ARG66412 anti-MED6 antibody (left) at 1:30 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200).
