ARG45182
anti-MCPIP1 / ZC3H12A antibody
anti-MCPIP1 / ZC3H12A antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MCPIP1 / ZC3H12A |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MCPIP1 / ZC3H12A |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human MCPIP1 / ZC3H12A. |
| Conjugation | Un-conjugated |
| Alternate Names | ZC3H12A; Zinc Finger CCCH-Type Containing 12A; Regnase-1; MCPIP1; Monocyte Chemotactic Protein-Induced Protein 1; Zinc Finger CCCH Domain-Containing Protein 12A; Endoribonuclease ZC3H12A; MCP-Induced Protein 1; FLJ23231; MCPIP-1; MCPIP; Reg1; Bifunctional Endoribonuclease And Deubiquitinase ZC3H12A; MCP-1 Treatment-Induced Protein; MCP Induced Protein 1; Ribonuclease ZC3H12A; DJ423B22.1; EC 3.1.-.- |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 73 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ZC3H12A |
| Gene Full Name | Zinc Finger CCCH-Type Containing 12A |
| Background | ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM, Mar 2008] |
| Function | Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angiogenesis. Functions as an endoribonuclease involved in mRNA decay. [UniProt] |
| Cellular Localization | Cytoplasm; Endoplasmic reticulum; Membrane; Nucleus. [UniProt] |
| Calculated MW | 66 kDa |
| PTM | Phosphoprotein; Ubl conjugation. [UniProt] |
Images (7) Click the Picture to Zoom In
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ARG45182 anti-MCPIP1 / ZC3H12A antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45182 anti-MCPIP1 / ZC3H12A antibody at 5 μg/ml dilution.
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ARG45182 anti-MCPIP1 / ZC3H12A antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45182 anti-MCPIP1 / ZC3H12A antibody at 5 ug/ml dilution.
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ARG45182 anti-MCPIP1 / ZC3H12A antibody WB image
Western blot: K562, Raji, Sw620, and Hela stained with ARG45182 anti-MCPIP1 / ZC3H12A antibody at 0.5 μg/ml dilution.
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ARG45182 anti-MCPIP1 / ZC3H12A antibody FACS image
Flow Cytometry: U87 stained with ARG45182 anti-MCPIP1 / ZC3H12A antibody at 1 µg/10^6 cells dilution.
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ARG45182 anti-MCPIP1 / ZC3H12A antibody IHC-P image
Immunohistochemistry: Rat lung stained with ARG45182 anti-MCPIP1 / ZC3H12A antibody at 5 μg/ml dilution.
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ARG45182 anti-MCPIP1 / ZC3H12A antibody WB image
Western blot: Rat spleen and rat kidney stained with ARG45182 anti-MCPIP1 / ZC3H12A antibody at 0.5 μg/ml dilution.
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ARG45182 anti-MCPIP1 / ZC3H12A antibody WB image
Western blot: Mouse thymus stained with ARG45182 anti-MCPIP1 / ZC3H12A antibody at 0.5 μg/ml dilution.
