ARG10028
anti-MCP3 antibody [1015]
anti-MCP3 antibody [1015] for Western blot and Human
Immune System antibody
Overview
| Product Description | Mouse Monoclonal antibody [1015] recognizes MCP3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1β, IL-8, MCAF, SAA and EGF. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1015 |
| Isotype | IgG2b, kappa |
| Target Name | MCP3 |
| Antigen Species | Human |
| Immunogen | Recombinant human MCP-3 (M.W. 8.5kDa containing 76 amino acids residues) |
| Conjugation | Un-conjugated |
| Alternate Names | MCP3; NC28; Monocyte chemotactic protein 3; MARC; Small-inducible cytokine A7; FIC; C-C motif chemokine 7; Monocyte chemoattractant protein 3; MCP-3; SCYA7; SCYA6 |
Application Instructions
| Application Note | Western Blot: This antibody, when used at concentration of 0.5-2μg/mL will allow visualization of 0.1 μg/lane of human MCP-3. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G affinity purified |
| Buffer | 0.01M PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL7 |
| Gene Full Name | chemokine (C-C motif) ligand 7 |
| Background | This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008] |
| Function | Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. [UniProt] |
| Research Area | Immune System antibody |
| Calculated MW | 11 kDa |
| PTM | O-glycosylated. |
