ARG44138
anti-MARS2 antibody
anti-MARS2 antibody for Western blot and Human,Mouse,Rat
Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease
Overview
| Product Description | Rabbit Polyclonal recognizes MARS2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MARS2 |
| Antigen Species | Human |
| Immunogen | Human MARS2 recombinant protein (Position: H143-A590). |
| Conjugation | Un-conjugated |
| Alternate Names | MARS2; Methionyl-TRNA Synthetase 2, Mitochondrial; MtMetRS; Methionine TRNA Ligase 2, Mitochondrial; Methionine--TRNA Ligase, Mitochondrial; EC 6.1.1.10; SPAX3; Methionine-TRNA Synthetase 2, Mitochondrial; Mitochondrial Methionyl-TRNA Synthetase; Methionyl-TRNA Synthetase 2; Methionine--TRNA Ligase 2; EC 6.1.1; COXPD25; MetRS |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q499X9 Mouse Methionine--tRNA ligase, mitochondrial Swiss-port # Q96GW9 Human Methionine--tRNA ligase, mitochondrial |
|---|---|
| Gene Symbol | MARS2 |
| Gene Full Name | Methionyl-TRNA Synthetase 2, Mitochondrial |
| Background | This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). |
| Function | ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met). |
| Cellular Localization | Mitochondrion |
| Research Area | Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease |
| Calculated MW | 67 kDa |
Images (3) Click the Picture to Zoom In
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ARG44138 anti-MARS2 antibody WB image
Western blot: HEL, HepG2 and K562 stained with ARG44138 anti-MARS2 antibody at 0.5 μg/ml dilution.
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ARG44138 anti-MARS2 antibody WB image
Western blot: C6 and PC-12 stained with ARG44138 anti-MARS2 antibody at 0.5 μg/ml dilution.
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ARG44138 anti-MARS2 antibody WB image
Western blot: Neuro-2a and Raw264.7 stained with ARG44138 anti-MARS2 antibody at 0.5 μg/ml dilution.
