Overview

Product Description	Mouse Monoclonal antibody recognizes MAGE-A3
Tested Reactivity	Hu
Tested Application	WB
Host	Mouse
Clonality	Monoclonal
Isotype	IgG
Target Name	MAGE-A3
Antigen Species	Human
Conjugation	Un-conjugated
Alternate Names	MAGEA3; MAGE Family Member A3; CT1.3; Melanoma-Associated Antigen 3; MAGE-3 Antigen; Antigen MZ2-D; MAGE3; HYPD; HIP8; Cancer/Testis Antigen Family 1, Member 3; Melanoma Antigen Family A3; Cancer/Testis Antigen 1.3; MGC14613; Melanoma Antigen Family A, 3; MAGEA6

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:1000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Purification	Protein A purification
Buffer	PBS with 0.09% sodium azide
Preservative	0.09% sodium azide
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Bioinformation

Database Links	GeneID: 4102 Human MAGEA3 Swiss-port # P43357 Human Melanoma-associated antigen 3
Gene Symbol	MAGEA3
Gene Full Name	MAGE Family Member A3
Background	This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
Function	Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. [Uniprot]
PTM	Ubl conjugation. [Uniprot]

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