ARG44864
anti-MAGE-A3 antibody
anti-MAGE-A3 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes MAGE-A3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | MAGE-A3 |
| Antigen Species | Human |
| Epitope | MPLEQRSQHC KPEEGLEARG EALGLVGAQA PATEEQEAAS SSSTLVEVTL GEVPAAESPD PPQSPQGASS LPTTMNYPLW SQSYEDSSNQ EEEGPSTFPD LESEFQAALS RKVAELVHFL LLKYRAREPV TKAEMLGSVV GNWQYFFPVI FSKASSSLQL VFGIELMEVD PIGHLYIFAT CLGLSYDGLL GDNQIMPKAG LLIIVLAIIA REGDCAPEEK IWEELSVLEV FEGREDSILG DPKKLLTQHF VQENYLEYRQ VPGSDPACYE FLWGPRALVE TSYVKVLHHM VKISGGPHIS YPPLHEWVLR EGEE |
| Conjugation | Un-conjugated |
| Alternate Names | MAGEA3; MAGE Family Member A3; CT1.3; Melanoma-Associated Antigen 3; MAGE-3 Antigen; Antigen MZ2-D; MAGE3; HYPD; HIP8; Cancer/Testis Antigen Family 1, Member 3; Melanoma Antigen Family A3; Cancer/Testis Antigen 1.3; MGC14613; Melanoma Antigen Family A, 3; MAGEA6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MAGEA3 |
| Gene Full Name | MAGE Family Member A3 |
| Background | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008] |
| Function | Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. [Uniprot] |
| PTM | Ubl conjugation. [Uniprot] |
Images (1) Click the Picture to Zoom In
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ARG44864 anti-MAGE-A3 antibody IHC-P image
Immunohistochemistry: Human testis stained with ARG44864 anti-MAGE-A3 antibody at 5 µg/mL dilution.
