ARG63269
anti-MAD3 / MXD3 antibody
anti-MAD3 / MXD3 antibody for ICC/IF,Immunohistochemistry and Human
Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes MAD3 / MXD3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC |
| Specificity | This antibody is expected to recognise isoform a (NP_112590.1) only. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MAD3 / MXD3 |
| Antigen Species | Human |
| Immunogen | C-QEHSYSHGGGAWL |
| Conjugation | Un-conjugated |
| Alternate Names | MYX; bHLHc13; Max dimerizer 3; Myx; Max dimerization protein 3; MAD3; BHLHC13; Max-interacting transcriptional repressor MAD3; Max-associated protein 3; Class C basic helix-loop-helix protein 13 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008] |
| Research Area | Gene Regulation antibody |
| Calculated MW | 23 kDa |
