ARG23896
anti-Lysozyme antibody [SB1 (BGN/06/961)]
anti-Lysozyme antibody [SB1 (BGN/06/961)] for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [SB1 (BGN/06/961)] recognizes Lysozyme |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IHC-P, WB |
| Specificity | The antibody recognizes lysozyme, an enzyme that is present in mucosal secretions such as saliva and tears that is involved with non-specific organism defence. It functions by hydrolyzing 1,2-beta linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues such as those found in the walls of various Gram-positive bacteria. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SB1 (BGN/06/961) |
| Isotype | IgG1 |
| Target Name | Lysozyme |
| Antigen Species | Human |
| Immunogen | Human lysozyme purified from urine. |
| Conjugation | Un-conjugated |
| Alternate Names | EC 3.2.1.17; Lysozyme C; LZM; 1,4-beta-N-acetylmuramidase C |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS and 0.09% Sodium azide. |
| Preservative | 0.09% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LYZ |
| Gene Full Name | lysozyme |
| Background | This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014] |
| Function | Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 17 kDa |
