ARG56497
anti-Leukotriene A4 hydrolase antibody
anti-Leukotriene A4 hydrolase antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Leukotriene A4 hydrolase |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Leukotriene A4 hydrolase |
| Antigen Species | Human |
| Immunogen | Recombinant Human Leukotriene A4 hydrolase. |
| Conjugation | Un-conjugated |
| Alternate Names | Leukotriene A; EC 3.3.2.6; 4; LTA-4 hydrolase; Leukotriene A-4 hydrolase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LTA4H |
| Gene Full Name | leukotriene A4 hydrolase |
| Background | The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
| Function | Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. [UniProt] |
| Calculated MW | 69 kDa |
| PTM | Phosphorylation at Ser-416 inhibits enzymatic activity. |
Images (1) Click the Picture to Zoom In
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ARG56497 anti-Leukotriene A4 hydrolase antibody WB image
Western blot: 1) Precision Plus Protein Standard, 2) 0.005 µg of LTA4 Hydrolase Standard, 3) 0.01 µg of LTA4 Hydrolase Standard, 4) 0.02 µg of LTA4 Hydrolase Standard, and 5) 50 µg of Raji cell lysate stained with ARG56497 anti-Leukotriene A4 hydrolase antibody.
