ARG42646

anti-LTBR / Lymphotoxin beta Receptor antibody

anti-LTBR / Lymphotoxin beta Receptor antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes LTBR / Lymphotoxin beta Receptor
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name LTBR / Lymphotoxin beta Receptor
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 420-435 of Human LTBR / Lymphotoxin beta Receptor (ATPSNRGPRNQFITHD).
Conjugation Un-conjugated
Alternate Names TNF-RIII; LT-BETA-R; Tumor necrosis factor receptor superfamily member 3; TNF-R-III; TNFR-III; TNFR-RP; TNFR3; D12S370; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; TNFCR; Tumor necrosis factor receptor type III; Lymphotoxin-beta receptor; TNFR2-RP; CD18; TNFRSF3

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:200 - 1:1000
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa and A549
Observed Size ~ 58 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide, 0.05% Thimerosal and 5% BSA.
Preservative 0.05% Sodium azide and 0.05% Thimerosal
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4055 Human LTBR

Swiss-port # P36941 Human Tumor necrosis factor receptor superfamily member 3

Gene Symbol LTBR
Gene Full Name lymphotoxin beta receptor (TNFR superfamily, member 3)
Background This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]
Function Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 47 kDa

Images (2) Click the Picture to Zoom In

  • ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human intestinal cancer tissue stained with ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody.

  • ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody WB image

    Western blot: 40 µg of HeLa and A549 whole cell lysates stained with ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody at 0.5 µg/ml dilution.