ARG23193

anti-LTBR / Lymphotoxin beta Receptor antibody [5G11b] (low endotoxin)

anti-LTBR / Lymphotoxin beta Receptor antibody [5G11b] (low endotoxin) for Flow cytometry,Functional study and Mouse

Overview

Product Description Azide free and low endotoxin Rat Monoclonal antibody [5G11b] recognizes LTBR / Lymphotoxin beta Receptor
Tested Reactivity Ms
Tested Application FACS, FuncSt
Host Rat
Clonality Monoclonal
Clone 5G11b
Isotype IgG2a
Target Name LTBR / Lymphotoxin beta Receptor
Antigen Species Mouse
Immunogen Recombinant extracellular domain of LTBR.
Conjugation Un-conjugated
Alternate Names TNF-RIII; LT-BETA-R; Tumor necrosis factor receptor superfamily member 3; TNF-R-III; TNFR-III; TNFR-RP; TNFR3; D12S370; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; TNFCR; Tumor necrosis factor receptor type III; Lymphotoxin-beta receptor; TNFR2-RP; CD18; TNFRSF3

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:50 - 1:100
FuncStAssay-dependent
Application Note FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Purification Note Low endotoxin
Buffer PBS.
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17000 Mouse LTBR

Swiss-port # P50284 Mouse Tumor necrosis factor receptor superfamily member 3

Gene Symbol LTBR
Gene Full Name lymphotoxin beta receptor (TNFR superfamily, member 3)
Background This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]
Function Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. [UniProt]
Calculated MW 47 kDa