ARG23193
anti-LTBR / Lymphotoxin beta Receptor antibody [5G11b] (low endotoxin)
anti-LTBR / Lymphotoxin beta Receptor antibody [5G11b] (low endotoxin) for Flow cytometry,Functional study and Mouse
Overview
| Product Description | Azide free and low endotoxin Rat Monoclonal antibody [5G11b] recognizes LTBR / Lymphotoxin beta Receptor |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS, FuncSt |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 5G11b |
| Isotype | IgG2a |
| Target Name | LTBR / Lymphotoxin beta Receptor |
| Antigen Species | Mouse |
| Immunogen | Recombinant extracellular domain of LTBR. |
| Conjugation | Un-conjugated |
| Alternate Names | TNF-RIII; LT-BETA-R; Tumor necrosis factor receptor superfamily member 3; TNF-R-III; TNFR-III; TNFR-RP; TNFR3; D12S370; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; TNFCR; Tumor necrosis factor receptor type III; Lymphotoxin-beta receptor; TNFR2-RP; CD18; TNFRSF3 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Purification Note | Low endotoxin |
| Buffer | PBS. |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P50284 Mouse Tumor necrosis factor receptor superfamily member 3 |
|---|---|
| Gene Symbol | LTBR |
| Gene Full Name | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| Background | This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] |
| Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. [UniProt] |
| Calculated MW | 47 kDa |
