ARG55377
anti-LSP1 antibody
anti-LSP1 antibody for Western blot and Human
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LSP1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LSP1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 121-149 of Human LSP1. |
| Conjugation | Un-conjugated |
| Alternate Names | Lymphocyte-specific protein 1; pp52; 52 kDa phosphoprotein; 47 kDa actin-binding protein; WP34; Lymphocyte-specific antigen WP34 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Daudi |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LSP1 |
| Gene Full Name | lymphocyte-specific protein 1 |
| Background | This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Function | May play a role in mediating neutrophil activation and chemotaxis. [UniProt] |
| Cellular Localization | Cell membrane; Peripheral membrane protein; Cytoplasmic side |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 37 kDa |
| PTM | Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis (By similarity). |
Images (1) Click the Picture to Zoom In
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ARG55377 anti-LSP1 antibody WB image
Western blot: 35 µg of Daudi cell lysate stained with ARG55377 anti-LSP1 antibody at 1:1000 dilution.
