ARG44403
anti-LIN9 antibody
anti-LIN9 antibody for ICC/IF,Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes LIN9 |
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Tested Reactivity | Hu |
Tested Application | ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | LIN9 |
Antigen Species | Human |
Immunogen | Human LIN9 recombinant protein (aa. sequence: F127-D542). |
Conjugation | Un-conjugated |
Alternate Names | LIN9; Lin-9 DREAM MuvB Core Complex Component; TGS; Type I Interferon Receptor Beta Chain-Associated Protein; Beta Subunit-Associated Regulator Of Apoptosis; TUDOR Gene Similar Protein; Rb Related Pathway Actor; PRB-Associated Protein; Protein Lin-9 Homolog; BARA; Lin-9 Homolog (C. Elegans) |
Application Instructions
Application Suggestion |
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Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
Preservative | 0.05% Sodium azide |
Stabilizer | 4% Trehalose |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
Database Links | |
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Gene Symbol | LIN9 |
Gene Full Name | Lin-9 DREAM MuvB Core Complex Component |
Background | This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Function | Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. |
Cellular Localization | Nucleus |
Calculated MW | 62 kDa |
PTM | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation |
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