ARG67104

anti-LCMT2 antibody

anti-LCMT2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes LCMT2
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name LCMT2
Antigen Species Human
Immunogen Human LCMT2 Synthesized peptide
Conjugation Un-conjugated
Alternate Names LCMT2; Leucine Carboxyl Methyltransferase 2; TYW4; KIAA0547; PPM2; TRNA(Phe) (7-(3-Amino-3-(Methoxycarbonyl)Propyl)Wyosine(37)-N)-Methoxycarbonyltransferase; TRNA(Phe) (7-(3-Amino-3-Carboxypropyl)Wyosine(37)-O)-Methyltransferase

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50-300
WB1:500-2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.5% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 296098 Rat LCMT2

GeneID: 329504 Mouse LCMT2

GeneID: 9836 Human LCMT2

Gene Symbol LCMT2
Gene Full Name Leucine Carboxyl Methyltransferase 2
Background The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW).
Function Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.
Calculated MW 76 kDa

Images (2) Click the Picture to Zoom In

  • ARG67104 anti-LCMT2 antibody IHC-P image

    Immunohistochemistry: Human lung squamous cell carcinoma stained with ARG67104 anti-LCMT2 antibody at 1:200 dilution.

  • ARG67104 anti-LCMT2 antibody WB image

    Western blot: PC-12 stained with ARG67104 anti-LCMT2 antibody at 1:1000 dilution.