ARG44422
anti-LCMT2 antibody
anti-LCMT2 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LCMT2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LCMT2 |
| Antigen Species | Human |
| Immunogen | Human LCMT2 recombinant protein (aa. sequence: A29-N595). |
| Conjugation | Un-conjugated |
| Alternate Names | LCMT2; Leucine Carboxyl Methyltransferase 2; TYW4; KIAA0547; PPM2; TRNA(Phe) (7-(3-Amino-3-(Methoxycarbonyl)Propyl)Wyosine(37)-N)-Methoxycarbonyltransferase; TRNA(Phe) (7-(3-Amino-3-Carboxypropyl)Wyosine(37)-O)-Methyltransferase |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LCMT2 |
| Gene Full Name | Leucine Carboxyl Methyltransferase 2 |
| Background | The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). |
| Function | Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. |
| Calculated MW | 76 kDa |
Images (4) Click the Picture to Zoom In
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ARG44422 anti-LCMT2 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44422 anti-LCMT2 antibody at 5 μg/mL dilution.
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ARG44422 anti-LCMT2 antibody WB image
Western blot: HeLa, THP-1 and SH-SY5Y stained with ARG44422 anti-LCMT2 antibody at 0.5 μg/mL dilution.
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ARG44422 anti-LCMT2 antibody WB image
Western blot: Mouse brain stained with ARG44422 anti-LCMT2 antibody at 0.5 μg/mL dilution.
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ARG44422 anti-LCMT2 antibody WB image
Western blot: Rat brain stained with ARG44422 anti-LCMT2 antibody at 0.5 μg/mL dilution.
