ARG44219
anti-L3MBTL3 antibody
anti-L3MBTL3 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes L3MBTL3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | L3MBTL3 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human L3MBTL3 |
| Conjugation | Un-conjugated |
| Protein Full Name | Lethal(3)malignant brain tumor-like protein 3 |
| Alternate Names | L3MBTL3; L3MBTL Histone Methyl-Lysine Binding Protein 3; KIAA1798; L3MBTL3, Histone Methyl-Lysine Binding Protein; Lethal(3)Malignant Brain Tumor-Like Protein 3; H-L(3)Mbt-Like Protein 3; L3mbt-Like 3; MBT-1; MBT1; L(3)Mbt-Like 3 (Drosophila); L(3)Mbt-Like Protein 3; L(3)Mbt-Like 3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96JM7 Human Lethal(3)malignant brain tumor-like protein 3 |
|---|---|
| Gene Symbol | L3MBTL3 |
| Gene Full Name | L3Mbtl Histone Methyl-Lysine Binding Protein 3 |
| Background | This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. |
| Function | Is a negative regulator of Notch target genes expression, required for RBPJ-mediated transcriptional repression. |
| Cellular Localization | Nucleus |
| Calculated MW | 88 kDa |
| PTM | Isopeptide bond, Phosphoprotein, Ubl conjugation |
Images (3) Click the Picture to Zoom In
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ARG44219 anti-L3MBTL3 antibody IHC-P image
Immunohistochemistry: Human bladder urothelial carcinoma stained with ARG44219 anti-L3MBTL3 antibody at 2 μg/mL dilution.
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ARG44219 anti-L3MBTL3 antibody WB image
Western blot: Jurkat, HEL, 293T and THP-1 stained with ARG44219 anti-L3MBTL3 antibody at 0.25 μg/mL dilution.
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ARG44219 anti-L3MBTL3 antibody FACS image
Flow Cytometry: U251 stained with ARG44219 anti-L3MBTL3 antibody at 1 μg/1x10^6 cells dilution.
