ARG63403
anti-KPNA1 / Importin alpha 5 antibody
anti-KPNA1 / Importin alpha 5 antibody for Western blot and Human
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes KPNA1 / Importin alpha 5 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KPNA1 / Importin alpha 5 |
| Antigen Species | Human |
| Immunogen | TTPGKENFRLKSY-C |
| Conjugation | Un-conjugated |
| Alternate Names | Importin subunit alpha-5; SRP1; Nucleoprotein interactor 1; IPOA5; RCH2; RAG cohort protein 2; SRP1-beta; NPI-1; Karyopherin subunit alpha-1 |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Jan 2009] |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 60 kDa |
| PTM | Polyubiquitinated in the presence of RAG1 (in vitro). |
Images (1) Click the Picture to Zoom In
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ARG63403 anti-KPNA1 / Importin alpha 5 antibody WB image
Western Blot: HeLa lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63403 anti-KPNA1 / Importin alpha 5 antibody at 1 µg/ml dilution.
