ARG63548
anti-KMT2D / MLL2 antibody
anti-KMT2D / MLL2 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes KMT2D / MLL2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Specificity | The immunizing peptide was designed from NP_003473.1. Since then the sequence has changed in the databases and currently differs at two locations in NP_003473.3. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KMT2D / MLL2 |
| Antigen Species | Human |
| Immunogen | DSQNLAGEDKDSQ-C |
| Conjugation | Un-conjugated |
| Alternate Names | KABUK1; Lysine N-methyltransferase 2D; TNRC21; AAD10; MLL2; KMS; CAGL114; MLL4; Myeloid/lymphoid or mixed-lineage leukemia protein 2; EC 2.1.1.43; Histone-lysine N-methyltransferase 2D; ALR; ALL1-related protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O14686 Human Histone-lysine N-methyltransferase 2D |
|---|---|
| Background | The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010] |
| Research Area | Gene Regulation antibody |
| Calculated MW | 593 kDa |
Images (2) Click the Picture to Zoom In
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ARG63548 anti-MLL2 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Placenta. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63548 anti-MLL2 antibody at 4 µg/ml dilution followed by HRP-staining.
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ARG63548 anti-MLL2 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Liver. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63548 anti-MLL2 antibody at 3.8 µg/ml dilution followed by HRP-staining.
