ARG64164

anti-KLK5 antibody

anti-KLK5 antibody for Western blot and Human,Mouse,Rat

Cancer antibody; Cell Biology and Cellular Response antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes KLK5
Tested Reactivity Hu, Ms, Rat
Predict Reactivity Cow, Dog
Tested Application WB
Specificity Reported variants represent identical protein (NP_036559.1; NP_001070959.1; NP_001070960.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name KLK5
Antigen Species Human
Immunogen KAGRDSCQGD
Conjugation Un-conjugated
Alternate Names Stratum corneum tryptic enzyme; Kallikrein-like protein 2; KLKL2; KLK-L2; Kallikrein-5; EC 3.4.21.-; SCTE

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 25818 Human KLK5

Swiss-port # Q9Y337 Human Kallikrein-5

Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Calculated MW 32 kDa

Images (2) Click the Picture to Zoom In

  • ARG64164 anti-KLK5 antibody WB image

    Western Blot: Human Prostate lysate (35 µg protein in RIPA buffer) stained with ARG64164 anti-KLK5 antibody at 0.1 µg/ml dilution.

  • ARG64164 anti-KLK5 antibody WB image

    Western blot: 35 µg of Human cerebellum (A), Mouse brain (B) and Rat brain (C) lysates (in RIPA buffer) stained with ARG64164 anti-KLK5 antibody at 2 µg/ml dilution and incubated at RT for 1 hour.