ARG11173
anti-KCNIP4 antibody
anti-KCNIP4 antibody for Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes KCNIP4 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KCNIP4 |
| Antigen Species | Mouse |
| Immunogen | A synthetic peptide (KTSSPAIQNSV) derived from the amino sequence acid residue 45-57 of mouse Kchip4, conjugated with KLH for immunization. |
| Conjugation | Un-conjugated |
| Alternate Names | KCNIP4; Potassium Voltage-Gated Channel Interacting Protein 4; KCHIP4; CALP; A-Type Potassium Channel Modulatory Protein 4; Kv Channel Interacting Protein 4; Kv Channel-Interacting Protein 4; Calsenilin-Like Protein; MGC44947; Potassium Channel-Interacting Protein 4; KChIP4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G affinity purified |
| Buffer | 0.01M PBS (pH 7.4) |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KCNIP4 |
| Gene Full Name | Potassium Voltage-Gated Channel Interacting Protein 4 |
| Background | This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. [UniProt] |
| Cellular Localization | Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane, Peroxisome. [UniProt] |
| Calculated MW | 29 kDa |
| PTM | Phosphoprotein. [UniProt] |
