ARG45330
anti-Inhibin beta B antibody [9M29]
anti-Inhibin beta B antibody [9M29] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody [9M29] recognizes Inhibin beta B |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 9M29 |
| Isotype | IgG1 |
| Target Name | Inhibin beta B |
| Antigen Species | Human |
| Immunogen | Recombinant Human Inhibin beta B. |
| Conjugation | Un-conjugated |
| Alternate Names | INHBB; Inhibin Subunit Beta B; Inhibin Beta B Chain; Activin Beta-B Chain; Inhibin, Beta B (Activin AB Beta Polypeptide); Activin AB Beta Polypeptide; Inhibin Beta B Subunit; Inhibin, Beta B; Inhibin, Beta-2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G chromatography |
| Buffer | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | INHBB |
| Gene Full Name | Inhibin Subunit Beta B |
| Background | This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients. [provided by RefSeq, Aug 2016] |
| Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 45 kDa |
| PTM | Cleavage on pair of basic residues; Disulfide bond; Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG45330 anti-Inhibin beta B antibody [9M29] IHC-P image
Immunohistochemistry: Human placental stained with ARG45330 anti-Inhibin beta B antibody [9M29].
