ARG10313
anti-Influenza A Virus Hemagglutinin antibody [C102]
anti-Influenza A Virus Hemagglutinin antibody [C102] for ELISA,ICC/IF,IHC-Frozen sections,Western blot and Influenza A virus
Microbiology and Infectious Disease antibody
Overview
| Product Description | Mouse Monoclonal antibody [C102] recognizes Influenza A Virus Hemagglutinin |
|---|---|
| Tested Reactivity | Influenza A |
| Tested Application | ELISA, ICC/IF, IHC-Fr, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | C102 |
| Isotype | IgG1 |
| Target Name | Influenza A Virus Hemagglutinin |
| Antigen Species | Mouse |
| Immunogen | Purified influenza virus type A strain H1N1 (strain: A/Kazakhstan/Seagull/470) |
| Conjugation | Un-conjugated |
Application Instructions
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G affinity purified. |
| Buffer | PBS (pH 7.4) and 0.1% Sodium azide |
| Preservative | 0.1% Sodium azide |
| Concentration | 1.0-2.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | HA |
|---|---|
| Gene Full Name | hemagglutinin |
| Function | Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity). [UniProt] |
| Research Area | Microbiology and Infectious Disease antibody |
| Calculated MW | 64 kDa |
Images (1) Click the Picture to Zoom In
-
ARG10313 anti-Influenza A Virus Hemagglutinin antibody [C102] ELISA image
ELISA: Specific activity of MAb C102 in ELISA with purified virus antigen A (H1N1). MAb C102 was obtained by use of avian influenza virus strain A (H1N1) as an immunogen and it is directed against relatively conservative H1 epitope. MAb cross reactivity pattern shows that it does not react with H3 and other haemagglutinins but interacts with H1 from human and avian influenza viruses, having indirect ELISA titers not less than 1:128 K.
Clone References
Localization and force analysis at the single virus particle level using atomic force microscopy.
A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategy.
WB /
Electrical detection of single viruses.
