ARG45230
anti-IRS2 antibody
anti-IRS2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IRS2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IRS2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human IRS2. |
| Conjugation | Un-conjugated |
| Alternate Names | IRS2; Insulin Receptor Substrate 2; |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 180 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IRS2 |
| Gene Full Name | Insulin Receptor Substrate 2 |
| Background | This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008] |
| Function | Signaling adapter protein that participates in the signal transduction from two prominent receptor tyrosine kinases, insulin receptor/INSR and insulin-like growth factor I receptor/IGF1R. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 137 kDa |
| PTM | Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation. [UniProt] |
Images (4) Click the Picture to Zoom In
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ARG45230 anti-IRS2 antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG45230 anti-IRS2 antibody at 2 μg/ml dilution.
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ARG45230 anti-IRS2 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45230 anti-IRS2 antibody at 5 ug/ml dilution.
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ARG45230 anti-IRS2 antibody WB image
Western blot: Hela stained with ARG45230 anti-IRS2 antibody at 0.5 μg/ml dilution.
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ARG45230 anti-IRS2 antibody FACS image
Flow Cytometry: 293T stained with ARG45230 anti-IRS2 antibody at 1 µg/10^6 cells dilution.
