ARG44848
anti-IRAG2 antibody
anti-IRAG2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes IRAG2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | IRAG2 |
| Antigen Species | Human |
| Epitope | LSGCIRMNDD PSMEENGVER VCPESLLQSR EYSSLPLPRH TSSTDGTITS SDPGLEILNM ASCDLDRNSL CKKEEDTRSA SPTIEAQGTS PAHDNIAFQD STSKDKTILN LEAKEEPETI EEHKKEHASG DSVVSPLPVT TVKSVNLRQS ENTSANEKEV EAEFLRLSLG FKCDWFTLEK RVKLEERSRD LAEENLKKEI TNCLKLLESL TPLCEDDNQA QEIIKKLEKS IKFLSQCAAR VASRAEMLGA INQESRVSKA VEVMIQHVEN LKRMYAKEHA ELEELKQVLL QNERSFNPLE |
| Conjugation | Un-conjugated |
| Alternate Names | IRAG2; Inositol 1,4,5-Triphosphate Receptor Associated 2; JAW1; LRMP; Lymphoid-Restricted Membrane Protein; Lymphoid Restricted Membrane Protein; Protein Jaw1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q12912 Human Lymphoid-restricted membrane protein |
|---|---|
| Gene Symbol | IRAG2 |
| Gene Full Name | Inositol 1,4,5-Triphosphate Receptor Associated 2 |
| Background | The protein encode dby this gene is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. The protein is localized to the cytoplasmic face of the endoplasmic reticulum. [provided by RefSeq, Jul 2008] |
| Function | Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules. [Uniprot] |
| Cellular Localization | Chromosome, Cytoplasm, Cytoskeleton, Endoplasmic reticulum, Membrane, Nucleus. [Uniprot] |
| PTM | Phosphoprotein. [Uniprot] |
Images (3) Click the Picture to Zoom In
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ARG44848 anti-IRAG2 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44848 anti-IRAG2 antibody at 7.5 µg/mL dilution.
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ARG44848 anti-IRAG2 antibody WB image
Western blot: Ramos stained with ARG44848 anti-IRAG2 antibody at 1 µg/mL dilution.
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ARG44848 anti-IRAG2 antibody IP image
Immunoprecipitation: Ramos lysate immunoprecipitated with 2.5 µg of ARG44848 anti-IRAG2 antibody.
