ARG42906
anti-INMT / TEMT antibody
anti-INMT / TEMT antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes INMT / TEMT |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | INMT / TEMT |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-263 of Human INMT / TEMT (NP_006765.4). |
| Conjugation | Un-conjugated |
| Alternate Names | Thioether S-methyltransferase; TEMT; Indolamine N-methyltransferase; EC 2.1.1.96; Indolethylamine N-methyltransferase; Aromatic alkylamine N-methyltransferase; Arylamine N-methyltransferase; Amine N-methyltransferase; EC 2.1.1.49 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse lung | ||||||
| Observed Size | ~ 30 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95050 Human Indolethylamine N-methyltransferase Swiss-port # P40936 Mouse Indolethylamine N-methyltransferase |
|---|---|
| Gene Symbol | INMT |
| Gene Full Name | indolethylamine N-methyltransferase |
| Background | N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream MINDY4 (aka FAM188B) gene. In rodents and other mammals such as cetartiodactyla this gene is in the opposite orientation compared to its orientation in human and other primates and this gene appears to have been lost in carnivora and chiroptera. [provided by RefSeq, Jul 2019] |
| Function | Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 29 kDa |
Images (2) Click the Picture to Zoom In
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ARG42906 anti-INMT / TEMT antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG42906 anti-INMT / TEMT antibody at 1:100 dilution.
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ARG42906 anti-INMT / TEMT antibody WB image
Western blot: 25 µg of Mouse lung lysate stained with ARG42906 anti-INMT / TEMT antibody at 1:3000 dilution.
