ARG65073
anti-INCA / CARD17 antibody
anti-INCA / CARD17 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes INCA / CARD17 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | INCA / CARD17 |
| Antigen Species | Human |
| Immunogen | C-NHLTTQDSQIVLPS |
| Conjugation | Un-conjugated |
| Alternate Names | INCA; Caspase-1 inhibitor INCA; Caspase recruitment domain-containing protein 17; Inhibitory caspase recruitment domain protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5XLA6 Human Caspase recruitment domain-containing protein 17 |
|---|---|
| Gene Symbol | CARD17 |
| Gene Full Name | caspase recruitment domain family, member 17 |
| Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody |
| Calculated MW | 12 kDa |
Images (1) Click the Picture to Zoom In
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ARG65073 anti-INCA / CARD17 antibody WB image
Western Blot: Human Kidney lysate (35 µg protein in RIPA buffer) stained with ARG65073 anti-INCA antibody at 0.5 µg/ml dilution.
