ARG56878

anti-IL33R / ST2 antibody

anti-IL33R / ST2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes IL33R / ST2
Tested Reactivity Hu, Ms
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IL33R / ST2
Antigen Species Mouse
Immunogen Synthetic peptide (16 aa) within aa. 40-90 of Mouse ST2. This peptide is common to all three known ST2 isoforms.
Conjugation Un-conjugated
Alternate Names IL33R; DER4; ST2V; T1; Interleukin-1 receptor-like 1; FIT-1; ST2; ST2L; Protein ST2

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF5 µg/ml
IHC-P5 µg/ml
WB1 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control 293 cells

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17082 Mouse IL1RL1

GeneID: 9173 Human IL1RL1

Swiss-port # P14719 Mouse Interleukin-1 receptor-like 1

Swiss-port # Q01638 Human Interleukin-1 receptor-like 1

Gene Symbol Il1rl1
Gene Full Name interleukin 1 receptor-like 1
Background The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Function Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. [UniProt]
Cellular Localization Cell membrane; Single-pass type I membrane protein.
Isoform B: Secreted
Calculated MW 63 kDa

Images (5) Click the Picture to Zoom In

  • ARG56878 anti-IL33R / ST2 antibody WB image

    Western blot: 293 cell lysate stained with ARG56878 anti-IL33R / ST2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.

  • ARG56878 anti-IL33R / ST2 antibody IHC-P image

    Immunohistochemistry: Human lung cancer tissue stained with ARG56878 anti-IL33R / ST2 antibody at 5 µg/ml.

  • ARG56878 anti-IL33R / ST2 antibody IHC image

    Immunohistochemistry: Human lung cancer tissue stained with ARG56878 anti-IL33R / ST2 antibody at 5 µg/ml.

  • ARG56878 anti-IL33R / ST2 antibody IHC-P image

    Immunohistochemistry: Human liver tissue stained with ARG56878 anti-IL33R / ST2 antibody at 5 µg/ml.

  • ARG56878 anti-IL33R / ST2 antibody ICC/IF image

    Immunofluorescence: Mouse kidney cells stained with ARG56878 anti-IL33R / ST2 antibody at 20 µg/ml.