ARG45387
anti-IL31 antibody
anti-IL31 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IL31 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IL31 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human IL31. |
| Conjugation | Un-conjugated |
| Alternate Names | Interleukin-31; IL-31 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 29 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IL31 |
| Gene Full Name | interleukin 31 |
| Background | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008] |
| Function | Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 18 kDa |
| PTM | Glycoprotein. [UniProt] |
Images (4) Click the Picture to Zoom In
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ARG45387 anti-IL31 antibody IHC-P image
Immunohistochemistry: Human colon cancer stained with ARG45387 anti-IL31 antibody at 1 μg/ml dilution.
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ARG45387 anti-IL31 antibody IHC-P image
Immunohistochemistry: Rat spleen stained with ARG45387 anti-IL31 antibody at 1 μg/ml dilution.
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ARG45387 anti-IL31 antibody WB image
Western blot: Rat spleen stained with ARG45387 anti-IL31 antibody at 0.5 μg/ml dilution.
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ARG45387 anti-IL31 antibody IHC-P image
Immunohistochemistry: Mouse spleen stained with ARG45387 anti-IL31 antibody at 1 μg/ml dilution.
