ARG42471
anti-IL2 Receptor gamma antibody
anti-IL2 Receptor gamma antibody for Flow cytometry,Immunohistochemistry and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IL2 Receptor gamma |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IL2 Receptor gamma |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 76-101 of Human IL2 Receptor gamma. |
| Conjugation | Un-conjugated |
| Alternate Names | IL-2R subunit gamma; IMD4; CD132; P64; p64; CD antigen CD132; Interleukin-2 receptor subunit gamma; SCIDX; CIDX; Cytokine receptor common subunit gamma; gammaC; SCIDX1; IL-2 receptor subunit gamma; IL-2RG |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P31785 Human Cytokine receptor common subunit gamma |
|---|---|
| Gene Symbol | IL2RG |
| Gene Full Name | interleukin 2 receptor, gamma |
| Background | The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010] |
| Function | Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770). [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 42 kDa |
Images (2) Click the Picture to Zoom In
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ARG42471 anti-IL2 Receptor gamma antibody IHC image
Immunofluorescence: 4% Paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized Human spleen tissue stained with ARG42471 anti-IL2 Receptor gamma antibody (green) at 1:25 dilution. DAPI (blue) for nuclear staining.
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ARG42471 anti-IL2 Receptor gamma antibody FACS image
Flow Cytometry: HL-60 cells stained with ARG42471 anti-IL2 Receptor gamma antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
