ARG56697
anti-IL17 / IL17A antibody
anti-IL17 / IL17A antibody for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Neutralizing,Western blot and Human
Overview
| Product Description | Goat Polyclonal antibody recognizes IL17 / IL17A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IHC-P, Neut, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IL17 / IL17A |
| Antigen Species | Human |
| Immunogen | E.coli derived Recombinant Human IL-17 (IL-17A). (MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA) |
| Conjugation | Un-conjugated |
| Alternate Names | IL-17A; Interleukin-17A; IL-17; CTLA8; IL17; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8 |
Application Instructions
| Application Suggestion |
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| Application Note | Sandwich ELISA: Sandwich ELISA: Recommended antibody pairs in sandwich immunoassay for IL17 / IL17A (capture - detection): ARG56697 - ARG56806 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IL17A |
| Gene Full Name | interleukin 17A |
| Background | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008] |
| Function | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. [UniProt] |
| Highlight | Related products: IL17 antibodies; IL17 ELISA Kits; IL17 recombinant proteins; Anti-Goat IgG secondary antibodies; Related news: HMGB1, a biomarker and therapeutic target in COVID-19 |
| Calculated MW | 18 kDa |
| PTM | Found both in glycosylated and nonglycosylated forms. |
Images (4) Click the Picture to Zoom In
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ARG56697 anti-IL17 / IL17A antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded sections of Human breast invasive ductal carcinoma. The recommended ARG56697 anti-IL17 / IL17A antibody concentration is 0.125 µg/ml - 0.25 µg/ml with an overnight incubation at 4°C. An HRP-labeled polymer detection system was used with a DAB chromogen. Antigen Retrieval: Boil tissue section in Sodium Citrate buffer (pH 6.0) followed by cooling at RT for 20 min.
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ARG56697 anti-IL17 / IL17A antibody WB image
Western blot: 250 - 0.24 ng of Human IL-17A stained with ARG56697 anti-IL17 / IL17A antibody, under reducing conditions.
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ARG56697 anti-IL17 / IL17A antibody WB image
Western blot: 250 - 0.24 ng of Human IL-17A stained with ARG56697 anti-IL17 / IL17A antibody, under non-reducing conditions.
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ARG56697 anti-IL17 / IL17A antibody standard curve image
Sandwich ELISA: ARG56697 anti-IL17 / IL17A antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with anti-IL17 / IL17A antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
