ARG65240
anti-IL12RB1 antibody
anti-IL12RB1 antibody for Western blot and Human
Immune System antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes IL12RB1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | This antibody is expected to recognize isoform 1 (NP_005526.1) only. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IL12RB1 |
| Antigen Species | Human |
| Immunogen | C-HVSVKNHSLDSVS |
| Conjugation | Un-conjugated |
| Alternate Names | Interleukin-12 receptor subunit beta-1; IL-12R-beta-1; IL12RB; IL-12R-BETA1; IL-12 receptor beta component; IL-12RB1; IL-12 receptor subunit beta-1; IMD30; CD212; IL-12R subunit beta-1; CD antigen CD212 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P42701 Human Interleukin-12 receptor subunit beta-1 |
|---|---|
| Background | The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Research Area | Immune System antibody |
| Calculated MW | 73 kDa |
Images (1) Click the Picture to Zoom In
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ARG65240 anti-IL12RB1 antibody WB image
Western Blot: Peripharal Blood Lymphocytes lysate (35 µg protein in RIPA buffer) stained with ARG65240 anti-IL12RB1 antibody at 0.3 µg/ml dilution.
