ARG66100
anti-IGFBP7 antibody
anti-IGFBP7 antibody for ELISA,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IGFBP7 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IGFBP7 |
| Antigen Species | Human |
| Immunogen | E. coli derived recombinant Human IGFBP7. (SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL) |
| Conjugation | Un-conjugated |
| Alternate Names | AGM; RAMSVPS; IBP-7; PSF; IGFBP-7; FSTL2; Tumor-derived adhesion factor; Insulin-like growth factor-binding protein 7; IGFBPRP1; TAF; MAC25; PGI2-stimulating factor; IGFBP-rP1; IGF-binding protein 7; IGFBP-7v; MAC25 protein; Prostacyclin-stimulating factor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q16270 Human Insulin-like growth factor-binding protein 7 |
|---|---|
| Gene Symbol | IGFBP7 |
| Gene Full Name | insulin-like growth factor binding protein 7 |
| Background | This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011] |
| Function | Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. [UniProt] |
| Calculated MW | 29 kDa |
| PTM | N-glycosylated. |
Images (3) Click the Picture to Zoom In
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ARG66100 anti-IGFBP7 antibody WB image
Western blot: 250 - 0.24 ng of Human IGF-BP7 stained with ARG66100 anti-IGFBP7 antibody, under non-reducing conditions.
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ARG66100 anti-IGFBP7 antibody standard curve image
Sandwich ELISA: ARG66100 anti-IGFBP7 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66101 anti-IGFBP7 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
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ARG66100 anti-IGFBP7 antibody WB image
Western blot: 250 - 0.24 ng of Human IGF-BP7 stained with ARG66100 anti-IGFBP7 antibody, under reducing conditions.
