ARG21502
anti-IFN gamma antibody [XMG1.2]
anti-IFN gamma antibody [XMG1.2] for ELISA,ELISPOT,Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Neutralizing,Western blot and Mouse
Publication1
Overview
| Product Description | Rat Monoclonal antibody [XMG1.2] recognizes IFN gamma |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, IHC-P, Neut, WB |
| Specificity | Mouse IFN-γ. |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | XMG1.2 |
| Isotype | IgG1, kappa |
| Target Name | IFN gamma |
| Antigen Species | Mouse |
| Immunogen | E. coli-expressed IFN-γ |
| Conjugation | Un-conjugated |
| Alternate Names | IFN-gamma; Interferon gamma; Immune interferon; IFG; IFI |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | BBS (pH 8.2) |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IFNG |
|---|---|
| Gene Full Name | interferon gamma |
| Background | This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015] |
| Function | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. [UniProt] |
| Highlight | Related products: IFN gamma antibodies; IFN gamma ELISA Kits; IFN gamma Duos / Panels; IFN gamma recombinant proteins; Anti-Rat IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
| Calculated MW | 19 kDa |
| PTM | Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. |
Images (3) Click the Picture to Zoom In
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ARG21502 anti-IFN gamma antibody [XMG1.2] WB image
Western blot: Mouse lysis stained with ARG21502 anti-IFN gamma antibody [XMG1.2].
From Hao Yu et al. Front Microbiol. (2023), doi: 10.3389/fmicb.2023.1126808, Fig. 4 (B).
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ARG21502 anti-IFN gamma antibody [XMG1.2] IHC-Fr image
Immunohistochemistry: Frozen section of Mouse pulmonary granuloma tissue stained with ARG21502 anti-IFN gamma antibody [XMG1.2].
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ARG21502 anti-IFN gamma antibody [XMG1.2] IHC-Fr image
Immunohistochemistry: Frozen section of acetone-fixed Mouse brain tissue stained with ARG21502 anti-IFN gamma antibody [XMG1.2].
Specific References
Fecal microbiota transplantation inhibits colorectal cancer progression: Reversing intestinal microbial dysbiosis to enhance anti-cancer immune responses
WB / Mouse
